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WHAT’S HAPPENING? WHAT DO I DO? What are SERMs? These oddly named medications are designed to have the wanted effects of estrogen without the unwanted ones. (SERM stands for selective estrogen receptor modulator.) Only one is available now, raloxifene (Evista®), but more are being developed. Raloxifene acts on bone and blood vessels but not on breasts, uterus or vagina. Initial research suggests that it protects against breast cancer, but further studies are needed to know how fully it does so. It also has some protective effect on the bones, and possibly on the heart, though probably not quite as much as estrogen itself. The great drawback of raloxifene is that it does not help the symptoms of menopause, in fact it may make them worse. Its use is mainly for women that are well past menopause, feel fine off estrogen and only need the long-term health protective effects. What is Menopause? |
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Copyright © 2008 Hormone Center of New York. Last modified:
03/23/08
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